Results
| PMID | 20858448 |
| Gene Name | AFM |
| Condition | Endometriosis |
| Association |
Associated |
| Population size | 242 |
| Population details | 242 reproductive-age women was to determine the concentration of afamin in the serum and peritoneal fluid of women with and without endometriosis |
| Sex | Female |
| Associated genes | afamin |
| Other associated phenotypes |
Endometriosis |
|
Fertil Steril. 2010 Dec;94(7):2923-6. doi: 10.1016/j.fertnstert.2010.05.008. Epub Seeber, Beata E| Czech, Theresa| Buchner, Hannes| Barnhart, Kurt T| Seger, Christoph| Daxenbichler, Guenter| Wildt, Ludwig| Dieplinger, Hans Department of Gynecologic Endocrinology and Reproductive Medicine, Medical University of Innsbruck, Innsbruck, Austria. beata.seeber@uki.at The objective of this case-control study of 242 reproductive-age women was to determine the concentration of afamin in the serum and peritoneal fluid of women with and without endometriosis and to test afamin as a diagnostic marker of endometriosis. Afamin levels were altered significantly in the peritoneal fluid of women with endometriosis compared with disease-free controls, correlated with vitamin E levels, and are consistent with increased oxidative stress in the peritoneal cavity of women with endometriosis. Mesh Terms: Adolescent| Adult| Ascitic Fluid/chemistry/*metabolism/pathology| Carrier Proteins/analysis/blood/*metabolism| Case-Control Studies| Endometriosis/blood/*metabolism/pathology| Female| Glycoproteins/analysis/blood/*metabolism| Humans| Middle Aged| |
|